💰 Unit Cost Winner GPT-4o $2.50/1M in · $10.00/1M out
⚡ Latency & Speed Winner GPT-4o 280ms TTFT · 100 tok/s
💻 Coding (SWE) Winner Claude 4.5 Sonnet 75.8% SWE-bench · 96% HumanEval
🧠 STEM Reasoning Winner Claude 4.5 Sonnet 84.2% GPQA · 97.5% MATH-500

Which model is better: Claude 4.5 Sonnet or GPT-4o?

GPT-4o is 16.7% cheaper for input tokens ($2.50 vs. $3.00 per 1M tokens) and $10.00 vs. $15.00 for output tokens (1.2x cost advantage). In terms of operational performance, GPT-4o delivers lower response latency at 280ms TTFT (100ms faster than Claude 4.5 Sonnet) with 100 vs. 84 tok/s throughput. Claude 4.5 Sonnet leads coding evaluations at 75.8% SWE-bench Verified vs. 48.0% for GPT-4o and 84.2% vs. 53.6% on GPQA Diamond.
Verified daily via automated API latency tests and official documentation.

Verified Performance & Unit Economics Delta (12 Dimensions)

Daily synchronized metrics across token pricing, prompt cache economics, latency, throughput, and 5 capability benchmarks.

Metric / Dimension Claude 4.5 Sonnet GPT-4o Net Delta / Advantage
Input Cost / 1M Tokens $3.00 $2.50 GPT-4o is 1.2x cheaper
Output Cost / 1M Tokens $15.00 $10.00 GPT-4o (33.3% lower)
Prompt Cache Read / 1M $0.300 $1.250 Claude 4.5 Sonnet is 4.2x cheaper
Prompt Cache Write / 1M $3.75 $2.50 GPT-4o is 1.5x cheaper
Context Window (Max Output) 205k (64k out) 131k (16k out) Claude 4.5 Sonnet (1.6x larger context)
Avg TTFT Response Latency 380ms 280ms GPT-4o (100ms faster)
Generation Speed (Throughput) 84 tok/s 100 tok/s GPT-4o (+16 tok/s faster)
SWE-bench Verified (Coding) 75.8% 48% Claude 4.5 Sonnet (+27.8% lead)
GPQA Diamond (PhD STEM) 84.2% 53.6% Claude 4.5 Sonnet (+30.6% lead)
MMLU-Pro (Multi-Discipline) 90.4% 75.9% Claude 4.5 Sonnet (+14.5% lead)
MATH-500 (Quantitative Logic) 97.5% 76.6% Claude 4.5 Sonnet (+20.9% lead)
Inference Value Score (IVR) 56.5 / 100 47.6 / 100 Claude 4.5 Sonnet (+8.9 pts)

Interactive Monthly Token Economics & ROI Forecaster

Model production workloads across prompt, completion, and cached context tokens, or switch models on the fly.

25.0M Tokens
500K 50M 250M 500M+
5.0M Tokens
100K 25M 75M 150M+
50% Cached
0% (Uncached) 25% 50% (Typical Agent) 95% Max

Estimated Monthly Spend

Claude 4.5 Sonnet $116.25

$3.00/1M in · $15.00/1M out

Prompt Cache: $0.300/1M read · $3.75/1M write

GPT-4o $96.88

$2.50/1M in · $10.00/1M out

Prompt Cache: $1.250/1M read · $2.50/1M write

Projected Monthly Cost Reduction
$19.38 / mo
(16.7% lower cost with GPT-4o)
Open Full Matchup Analysis →
A

When to Choose Claude 4.5 Sonnet

Choose Claude 4.5 Sonnet (Anthropic) for end-to-end autonomous coding agents, complex multi-file debugging, browser/GUI automation, and high-precision technical writing — offering a 204k context window, 380ms TTFT, and $3.00/1M input pricing ($0.300/1M cached reads).

B

When to Choose GPT-4o

Choose GPT-4o (OpenAI) for general enterprise assistants, multimodal customer support, and structured JSON output pipelines — offering a 131k context window, 280ms TTFT, and $2.50/1M input pricing ($1.250/1M cached reads).

Related Questions & Decision Factors

Which is cheaper: Claude 4.5 Sonnet or GPT-4o?

GPT-4o is cheaper at $2.50/1M input tokens ($10.00/1M output) compared to $3.00/1M input ($15.00/1M output) for Claude 4.5 Sonnet.

Which model has lower TTFT latency and higher tok/s throughput: Claude 4.5 Sonnet or GPT-4o?

GPT-4o delivers faster first-token latency at 280ms TTFT (100 tok/s throughput) compared to 380ms TTFT (84 tok/s) for Claude 4.5 Sonnet.

How do Claude 4.5 Sonnet and GPT-4o compare on SWE-bench coding and GPQA Diamond reasoning?

On SWE-bench Verified software engineering, Claude 4.5 Sonnet scores 75.8% versus 48% for GPT-4o. On GPQA Diamond graduate-level STEM reasoning, Claude 4.5 Sonnet scores 84.2% versus 53.6% for GPT-4o (and 97.5% vs 76.6% on MATH-500).

When should you choose Claude 4.5 Sonnet?

Choose Claude 4.5 Sonnet (Anthropic) for end-to-end autonomous coding agents, complex multi-file debugging, browser/GUI automation, and high-precision technical writing — offering a 204k context window, 380ms TTFT, and $3.00/1M input pricing ($0.300/1M cached reads).

When should you choose GPT-4o?

Choose GPT-4o (OpenAI) for general enterprise assistants, multimodal customer support, and structured JSON output pipelines — offering a 131k context window, 280ms TTFT, and $2.50/1M input pricing ($1.250/1M cached reads).

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